Interstitial Cystitis, Bladder Syndrome Pain in

Interstitial Cystitis is a chronic condition characterized by a combination of bladder pain and sometimes pain in the pelvis. Pain is felt a burning sensation can range from mild to severe pain.
Interstitial Cystitis is also called painful bladder syndrome and most attacking women. Interstitial Cystitis can have an adverse effect of long-term quality of life.
Symptom
The signs and symptoms of Interstitial Cystitis varies from person to person. Interstitial Cystitis Symptoms include:1. Pain in the hip or between the vagina and anus in women or between the scrotum and anus in men.2. Chronic pelvic pain.3. Frequent urination, but in small quantities and begin on the day and night. In severe cases can even urinate 60 times a day.4. Pain during intercourse.
Interstitial Cystitis symptoms similar to chronic urinary tract infection, but urine does not contain the bacteria. Worsening of symptoms may occur if the Interstitial Cystitis patients experienced urinary tract infections.
Cause
The bladder is a muscular organ formed of hollow, shaped like a balloon and for maintaining the urine until it is ready to be emptied. In adults, the bladder expands until full and then give a signal to the brain if it's time to urinate.
The signal is communicated via the pelvic nerve. In Interstitial Cystitis, nerve signals interfere so that people feel the need to urinate more frequently and with smaller volumes than normal.
It is possible that many people with Interstitial Cystitis also have defects in the protective lining (epithelium) their bladder. A leak in the epithelium allows toxic substances in the urine irritate the bladder wall.
Treatments and drugs
A. Oral medications that can relieve the symptoms of Interstitial Cystitis include:1. Ibuprofen (Advil, Motrin, others), naproxen (Aleve, Anaprox), and nonsteroidal anti-inflammatory drugs, for pain relief.2. Tricyclic antidepressants such as amitriptyline or imipramine (Tofranil), to help relax your bladder and block pain.3. Antihistamines such as diphenhydramine (Benadryl, others) and loratadine (Claritin, others), to relieve often to urinate and relieve other symptoms.
4. Pentosan (Elmiron), an oral drug that has been to treat Interstitial Cystitis. This drug may take up to six months to reduce urinary frequency. The side effects include gastrointestinal disturbances and mild hair loss that will improve when stopped taking medication. This drug has not been studied in pregnant women.
B. Nerve stimulation
Transcutaneous electrical nerve stimulation (TENS) uses mild electrical voltage to relieve pelvic pain and reduce urinary frequency. The power cord is placed under the back or just above the pubic area.
Electric voltage is given for a few minutes or hours, twice or more a day. In some cases, TENS devices can be inserted into the woman's vagina or anus men.
The scientists believe that TENS may relieve pain and urinary frequency associated with Interstitial Cystitis by increasing blood flow to the bladder, strengthens the muscles that help control the bladder or triggering the release of substances that block pain.
Another possible treatment is to stimulate the sacral nerve. Sacral nerve modulation (the main route between the spinal cord and nerves in the bladder) can reduce the feeling of wanting to urinate immediately.
The method is a thin wire placed near the sacral nerves and provides electrical impulses to the bladder, similar to a pacemaker. If the procedure is successful in reducing symptoms, a permanent device that can be surgically implanted.
C. Inflating the bladderYou do this by stretching the bladder using a water or gas. The procedure can be used as a treatment if the response lasted.
D. Drugs that are implanted into the bladderDimethyl sulfoxide, or DMSO, (Rimso-50) is placed into the bladder through a thin flexible tube (catheter) and inserted through the urethra. The solution is sometimes mixed with other drugs such as local anesthetics.
Having been in the bladder for 15 minutes, the solution removed through urination. This method can reduce inflammation and prevent muscle contractions that cause the symptoms of Interstitial Cystitis.
The new treatment by injecting the bladder using a solution containing a mixture of drugs: lidocaine, sodium bicarbonate and pentosan or heparin can be used to reduce symptoms.
E. OperationDoctors rarely use surgery as the treatment of Interstitial Cystitis due to removal of part or all of the bladder does not relieve pain and other complications can cause. The operation is usually performed only after other treatments have failed.
The options include:1. Bladder augmentation. Eliminates the damaged portion of the bladder and replaced it with a piece of the colon. This operation still leaves little symptoms of pain and some people still need to empty the bladder with a catheter multiple times a day.2. Fulguration. Insertion of the instrument through the urethra to burn ulcers that may arise due to Interstitial Cystitis.3. Resection. Insertion of the instrument through the urethra to cut ulcers.
Sources: MayoClinic